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Which Two-sample t-test Would You Use?

For each of these research questions, would you use a paired-sample t-test or an independent two-sample t-test? If each case, we are looking for a significant difference.

1. Does a new drug reduce chloresterol?
    
2. Are the heights and weights of identical twins significantly different?
    
3. Which of two brands of house paint lasts longer?
    
4. Do men or women drivers get better gas mileage?
    
5. Which of two new web sites under development is more user friendly?
    
6. Which of two paper brands is thicker, White or Yellow, for Project 1?