| Authors: |
Jennifer Van
Puymbrouck, David Angulo, Kevin Drew, Lee Ann Hollenbeck, Dominic
Battre, Alex Schilling, David Jabon, Gregor von Laszewski |
| Abstract: |
Proteomic researchers who
study mass spectrometry data have expressed a need for an accurate
public database of empirically derived curated mass spectrum
information. Lack of such a database limits proteomic researchers in
their ability to identify and study proteins. Until recently, storage
space and computing power has been the limiting factor in developing
tools to handle the vast amount of mass spectrometry information. Now,
the resources are available to store, organize, and analyze mass
spectrometry information. The Illinois Bio-Grid Mass Spectrometry
Database is a database of empirically derived tandem mass spectra of
peptides created to provide researchers with an organized and searchable
database of curated spectrum information to allow more accurate protein
identification. This paper will discuss the methods used to import the
mass spectra into the Illinois Bio-Grid Mass Spectrometry Database, as
well as the database requirements, motivation, use cases, design, and
results. |